Protein name:
Glutamate decarboxylase 2;
Alternative:
Glutamate decarboxylase 65 kDa isoform;65 kDa glutamic acid decarboxylase(GAD-65);
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Catalyzes the production of GABA.
Subcellular Location:
Cytoplasm
cytosol
Cytoplasmic vesicle
Cell junction
synapse
presynaptic cell membrane
Lipid-anchor
Golgi apparatus membrane
Peripheral membrane protein
Cytoplasmic side
Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
Protein Attributes:
50:
MASPGSGFWS | FGSEDGSADP | ENPGTARAWC | QVAQKFTGGI | GNKLCALLYG |
100:
DSGKPAEGGG | SVTSRAATGK | VACTCDQKPC | NCPKGDVNYA | FLHATDLLPA |
150:
CDGERPTLAF | LQDVMNILLQ | YVVKSFDRST | KVIDFHYPNE | LLQEYNWELA |
200:
DQPQNLEEIL | THCQTTLKYA | IKTGHPRYFN | QLSTGLDMVG | LAADWLTSTA |
250:
NTNMFTYEIA | PVFVLLEYVT | LKKMREIIGW | PGGSGDGIFS | PGGAISNMYA |
300:
MLIARYKMFP | EVKEKGMAAV | PRLIAFTSEH | SHFSLKKGAA | ALGIGTDSVI |
350:
LIKCDERGKM | IPSDLERRIL | EVKQKGFVPF | LVSATAGTTV | YGAFDPLLAV |
400:
ADICKKYKIW | MHVDAAWGGG | LLMSRKHKWK | LSGVERANSV | TWNPHKMMGV |
450:
PLQCSALLVR | EEGLMQSCNQ | MHASYLFQQD | KHYDLSYDTG | DKALQCGRHV |
500:
DVFKLWLMWR | AKGTTGFEAH | IDKCLELAEY | LYTIIKNREG | YEMVFDGKPQ |
550:
HTNVCFWFVP | PSLRTLEDNE | ERMSRLSKVA | PVIKARMMEY | GTTMVSYQPL |
585:
GDKVNFFRMV | ISNPAATHQD | IDFLIEEIER | LGQDL
Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Glutamate decarboxylase 2
ELISA Kit for Mouse Glutamate decarboxylase 2
ELISA Kit for Mouse Glutamate decarboxylase 2
ELISA Kit for Mouse Glutamate decarboxylase 2
ELISA Kit for Mouse Glutamate decarboxylase 2
CLIA Kit for Mouse Glutamate decarboxylase 2
CLIA Kit for Mouse Glutamate decarboxylase 2
CLIA Kit for Mouse Glutamate decarboxylase 2
CLIA Kit for Mouse Glutamate decarboxylase 2
CLIA Kit for Mouse Glutamate decarboxylase 2
Polyclonal Antibody for Mouse Glutamate decarboxylase 2
Polyclonal Antibody for Mouse Glutamate decarboxylase 2
Polyclonal Antibody for Mouse Glutamate decarboxylase 2
Polyclonal Antibody for Mouse Glutamate decarboxylase 2
Polyclonal Antibody for Mouse Glutamate decarboxylase 2
Monoclonal Antibody for Mouse Glutamate decarboxylase 2
Monoclonal Antibody for Mouse Glutamate decarboxylase 2
Monoclonal Antibody for Mouse Glutamate decarboxylase 2
Monoclonal Antibody for Mouse Glutamate decarboxylase 2
Monoclonal Antibody for Mouse Glutamate decarboxylase 2
Protein for Mouse Glutamate decarboxylase 2
Protein for Mouse Glutamate decarboxylase 2
Protein for Mouse Glutamate decarboxylase 2
Protein for Mouse Glutamate decarboxylase 2
Protein for Mouse Glutamate decarboxylase 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain:
C57BL/6.
tissue:
Brain.
-
2.
"Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures."
Asada H.
,
Kawamura Y.
,
Maruyama K.
,
Kume H.
,
Ding R.G.
,
Ji F.Y.
,
Kanbara N.
,
Kuzume H.
,
Sanbo M.
,
Yagi T.
,
Obata K.
Biochem. Biophys. Res. Commun.229:891-895(1996)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain:
C57BL/6.
tissue:
Brain.
-
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue:
Eye.
-
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 175-379
tissue:
Brain.